Author

A. Vogt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Approach:statistical model· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:transcription & RNA processing· 2

Frequent Co-Authors

E. Platanitis· 2 shared T. Decker· 2 shared A. P. Wiita· 1 shared A. Padzik· 1 shared A. R. S. J. Geetha· 1 shared A. Ravi Sundar Jose Geetha· 1 shared A. Sommer· 1 shared C. Hong· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersImmunology

E. Platanitis

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Dynamic control of gene expression by ISGF3 and IRF1 duringIFNbeta and IFNgamma signaling

A. Ravi Sundar Jose Geetha, K. Fischer, G. Smesnik, A. Vogt, E. Platanitis, M. Muller, M. Farlik, T. Decker

The paper shows that IFN-I and IFN-gamma produce distinct transcriptomes over time due to different roles of ISGF3 and IRF1 in enhancer activation and chromatin accessibility.

bioRxiv · Jun 28, 2023Immunology

Transcriptional landscape of DTP-DTEP transition reveals DUSP6 as a driver of HER2 inhibitor tolerance via Neuregulin/HER3 axis

M. Momeny, M. Tienhaara, D. Chakroborty, M. Sharma, R. Varjus, J. Merisaari, A. Padzik, A. Vogt, I. Paatero, K. Kurppa, K. Elenius, T. D. Laajala, J. Westermarck

This study identifies DUSP6 as a driver of HER2 inhibitor tolerance through the Neuregulin/HER3 axis by analyzing the transcriptional changes during the DTP-DTEP transition in HER2+ breast cancer cells.

bioRxiv · Jun 14, 2023 · PreprintCancer Biology

YidC from Escherichia coli forms an ion-conducting pore upon activation by ribosomes.

D. G. Knyazev, L. Winter, A. Vogt, S. Posch, C. Siligan, N. Goessweiner-Mohr, N. Hagleitner-Ertugrul, H.-G. Koch, P. Pohl

The paper shows that E. coli YidC forms an ion-conducting pore when bound to a ribosome or ribosome-nascent chain complex, suggesting an alternative mechanism for membrane protein insertion.

bioRxiv · May 10, 2023Biophysics

Interferons Reshape the 3D Conformation and Accessibility of Macrophage Chromatin

E. Platanitis, S. Güner, A. R. S. J. Geetha, L. Boccuni, A. Vogt, M. Novatchkova, A. Sommer, M. Müller, T. Decker

This study shows that type I and type II interferons induce similar epigenomic and transcriptional changes in macrophages, including 3D chromatin rearrangements and increased DNA accessibility at ISG loci.

bioRxiv · Mar 9, 2021Immunology

Signaling input from divergent pathways subverts malignant B-cell transformation

L. N. Chan, M. A. Murakami, M. E. Robinson, R. Caeser, T. Sadras, J. Lee, K. N. Cosgun, K. Kume, V. Khairnar, G. Xiao, M. Ahmed, E. Aghania, G. Deb, C. Hurtz, S. Shojaee, , M. Muschen

This study shows that malignant B-cell transformation requires convergence on a single oncogenic pathway, while divergent pathways can subvert transformation and are targets for new therapeutic strategies.

bioRxiv · Mar 12, 2020Cancer Biology