Author

A. R. Sahoo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

M. Buck· 2 shared A. W. Smith· 1 shared F. N. Barrera· 1 shared J. A. Rybak· 1 shared P. C. T. Souza· 1 shared R. J. Pyron· 1 shared S. B. Pitts· 1 shared S. Guleryuz· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCell Biology

M. Buck

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Author profile →

2 papers

Recent·Most cited

Allosteric inhibition of the epidermal growth factor receptor through disruption of transmembrane interactions

J. A. Rybak, A. R. Sahoo, S. Kim, R. J. Pyron, S. B. Pitts, S. Guleryuz, A. W. Smith, M. Buck, F. N. Barrera

This study develops a pH-responsive peptide, PET1, that inhibits EGFR-mediated cell migration by disrupting transmembrane interactions, offering a new strategy for targeting RTKs with reduced side effects.

bioRxiv · Oct 31, 2022Cell Biology

Transmembrane region dimer structures of Type 1 receptors readily sample alternate configurations: MD simulations using the Martini 3 coarse grained model compared to AlphaFold2 Multimer

A. R. Sahoo, P. C. T. Souza, Z. Meng, M. Buck

This study compares Martini 3 coarse-grained MD simulations of TM receptor dimers with AlphaFold2 Multimer and NMR structures, finding that Martini 3 samples alternate configurations that interconvert.

bioRxiv · Sep 10, 2021 · PreprintBiophysics