ImmunologybioRxiv
Targeting macrophages with CAR-T cells delays solid tumor progression and enhances anti-tumor immunity
A. R. Sanchez-Paulete, J. Mateus-Tique, G. Mollaoglu…·B. D. Brown
This study shows that CAR-T cells targeting macrophages delay tumor growth and improve survival in mouse models of solid tumors by enhancing anti-tumor immunity.
DOI 10.1158/2326-6066.cir-21-1075