Author

A. R. Shim

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Assay:imaging· 1 Approach:statistical model· 1

Frequent Co-Authors

I. Szleifer· 2 shared L. M. Almassalha· 2 shared V. Backman· 2 shared A. Eshein· 1 shared C. L. Dunton· 1 shared E. M. Pujadas· 1 shared I. C. Ye· 1 shared J. A. Pritchard· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersBiophysics

I. Szleifer

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2 papers

Recent·Most cited

Formamide denaturation of double-stranded DNA for fluorescence in situ hybridization (FISH) distorts nanoscale chromatin structure

A. R. Shim, J. Frederick, E. M. Pujadas, T. Kuo, I. C. Ye, J. A. Pritchard, C. L. Dunton, P. Carrillo Gonzalez, N. Acosta, S. Jain, N. M. Anthony, L. M. Almassalha, I. Szleifer, V. Backman

This study shows that formamide in 3D FISH distorts nanoscale chromatin structure, while alternative methods like RASER-FISH and CRISPR-Sirius have minimal impact.

bioRxiv · Mar 1, 2024Biophysics

Physical and data structure of 3D genome

K. Huang, Y. Li, A. R. Shim, R. J. Nap, V. Agrawal, R. K. A. Virk, A. Eshein, L. M. Almassalha, V. Backman, I. Szleifer

This paper proposes a tree-like data structure for the 3D genome to explain its physical properties and folding principles.

bioRxiv · Apr 2, 2019Biophysics