L. M. Almassalha

The paper examines chromosomal organization changes during myogenesis and finds differences between normal myogenic cells and rhabdomyosarcoma cells.

This study introduces a mesoscale model to show how transcription and epigenetic reactions regulate heterochromatin domain sizes, finding that transcription loss increases domain size and compaction.

This paper proposes a tree-like data structure for the 3D genome to explain its physical properties and folding principles.

This paper introduces a single-scan optical coherence tomography angiography method using spectral contrast to image vessels without requiring multiple acquisitions.

This paper introduces a multimodal interferometric imaging platform to study nanoscale structure and macromolecular dynamics in live cells, revealing a new phenomenon called cellular paroxysm induced by UV light.

This study shows that extracellular cations alter nuclear shape and mechanics through heterochromatin formation, rescuing nuclear morphology in disease models.

The paper shows that chromatin histone modifications affect nuclear rigidity and morphology independently of lamins, inducing or suppressing nuclear blebs through changes in chromatin compaction.