MicrobiologybioRxiv
Rational Designed Hybrid Peptides Show up to a 6-fold Increase in Antimicrobial Activity and Demonstrate Different Ultrastructural Changes as the Parental Peptides measured by BioSAXS
K. Hilpert, J. Gani, C. Rumancev…·A. Rosenhahn
The paper designs hybrid peptides combining proline-rich and arginine-isoleucine-rich peptides, showing up to 6-fold increased antimicrobial activity and distinct structural effects compared to parental peptides.
DOI 10.3389/fphar.2021.769739