Sclerostin directly stimulates osteocyte synthesis of fibroblast growth factor-23
N. Ito, M. Prideaux, A. R. Wijenayaka, D. Yang, R. T. Ormsby, L. F. Bonewald, G. J. Atkins
This study shows sclerostin directly increases FGF23 production in osteocytes, contributing to phosphate homeostasis regulation.
bioRxiv · Oct 29, 2020Physiology