Author

A. Roisin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. Cimarelli· 1 shared C. Rocchi· 1 shared F. Fiorini· 1 shared F. Gerard-Baraggia· 1 shared M. Mghezzi-Habellah· 1 shared P. Gouet· 1 shared P.-D. Coureux· 1 shared S. Deymier· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

A. Cimarelli

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1 paper

Recent·Most cited

The SARS-CoV-2 nucleocapsid protein inhibits the cellular Nonsense-Mediated mRNA Decay (NMD) pathway preventing the full enzymatic activation of UPF1.

V. Nuccetelli, M. Mghezzi-Habellah, S. Deymier, A. Roisin, F. Gerard-Baraggia, C. Rocchi, P.-D. Coureux, P. Gouet, A. Cimarelli, V. Mocquet, F. Fiorini

This study shows that SARS-CoV-2 Np inhibits NMD by blocking UPF1 activity and disrupting UPF1/UPF2 complex formation, revealing a novel mechanism of viral evasion.

bioRxiv · Jul 16, 2024 · PreprintBiochemistry