Author

C. Rocchi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1 Organism:human· 1

Frequent Co-Authors

F. Fiorini· 2 shared P. Gouet· 2 shared A. Cimarelli· 1 shared A. E. Miele· 1 shared A. L. Johnson· 1 shared A. Roisin· 1 shared B. Becher· 1 shared C. C. Bain· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersBiochemistry

F. Fiorini

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The SARS-CoV-2 nucleocapsid protein inhibits the cellular Nonsense-Mediated mRNA Decay (NMD) pathway preventing the full enzymatic activation of UPF1.

V. Nuccetelli, M. Mghezzi-Habellah, S. Deymier, A. Roisin, F. Gerard-Baraggia, C. Rocchi, P.-D. Coureux, P. Gouet, A. Cimarelli, V. Mocquet, F. Fiorini

This study shows that SARS-CoV-2 Np inhibits NMD by blocking UPF1 activity and disrupting UPF1/UPF2 complex formation, revealing a novel mechanism of viral evasion.

bioRxiv · Jul 16, 2024 · PreprintBiochemistry

CSF1R-dependent macrophages in the salivary gland are essential for epithelial regeneration following radiation-induced injury

J. G. McKendrick, G.-R. Jones, S. S. Elder, E. Mercer, M. S. Magalhaes, C. Rocchi, L. M. Hegarty, A. L. Johnson, C. Schneider, B. Becher, C. Pridans, N. A. Mabbott, Z. Liu, F. Ginhoux, M. Bajenoff, , E. Emmerson

This study identifies CSF1R-dependent macrophages as critical for epithelial regeneration after radiation-induced salivary gland injury.

bioRxiv · Jun 12, 2022Immunology

The HIV-1 Integrase C-Terminal domain induces TAR RNA structural changes promoting Tat binding.

C. Rocchi, C. Louvat, A. E. Miele, J. Batisse, C. Guillon, L. Ballut, D. Lener, M. Negroni, M. Ruff, P. Gouet, F. Fiorini

This study shows that the HIV-1 Integrase C-terminal domain interacts with TAR RNA, inducing structural changes that facilitate Tat binding and displace IN from TAR.

bioRxiv · Oct 21, 2021Biochemistry