BiochemistrybioRxivPreprint
Mycobacterium tuberculosis DNA-repair helicase UvrD1 is activated by redox-dependent dimerization via a conserved 2B domain cysteine.
A. Chadda, D. Jensen, E. J. Tomko…·E. A. Galburt
This study shows that Mtb UvrD1 dimerizes under oxidative conditions, enhancing its DNA unwinding activity through a conserved cysteine in the 2B domain.
DOI 10.1101/2021.10.26.465901