Cancer BiologybioRxivPreprint
The IRE1α-endonuclease regulates PD-1 expression through a novel XBP1/miRNA-34a axis within Natural Killer cells
K. Bednarska, G. Thillaiyampalam, S. Mujaj…·A. S. Cristino
This study identifies a novel IRE1α-endonuclease regulated XBP1/miR-34a axis that modulates PD-1 expression in NK-cells, with implications for cancer immunotherapy.
DOI 10.1101/2023.02.26.530063