Author

A. Schmidbauer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

D. Grohmann· 2 shared L. Jakob· 2 shared E. Woerle· 1 shared F. Fettes· 1 shared F. Welzel· 1 shared G. Zinner· 1 shared M. Rutkauskas· 1 shared P. Aldag· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 26 mutual co-author links

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2 shared papersBiophysics

D. Grohmann

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2 papers

Recent·Most cited

Probing the stability of the SpCas9-DNA complex after cleavage

P. Aldag, F. Welzel, L. Jakob, A. Schmidbauer, M. Rutkauskas, F. Fettes, D. Grohmann, R. Seidel

This study investigates the stability of SpCas9-DNA complexes after cleavage using single-molecule magnetic tweezers, finding that post-cleavage states are more stable than pre-cleavage states.

bioRxiv · Aug 4, 2021Biophysics

Decoupling the bridge helix of Cas12a results in a reduced trimming activity and impaired conformational transitions

E. Woerle, L. Jakob, A. Schmidbauer, G. Zinner, D. Grohmann

This study shows that modifying the bridge helix of Cas12a reduces its trimming activity and affects its conformational changes.

bioRxiv · Feb 25, 2021Biochemistry