Intratumoral administration of recombinant murine interleukin-12 prevents tumor progression and bone invasion
T. Uchihashi, S. Kasahara, T. Inubushi, K. Kurioka, A. Sugauchi, K. Miyagawa, M. Kogo, S. Tanaka
This study shows that intratumoral IL-12 injection reduces tumor growth and bone resorption in a mouse model of oral squamous cell carcinoma through a T cell-dependent mechanism.
bioRxiv · May 26, 2023Cancer Biology