Epidermal activation of Hedgehog signaling establishes an immunosuppressive microenvironment in basal cell carcinoma by modulating skin immunity
S. Grund-Groeschke, D. Ortner, A. Szenes-Nagy, N. Zaborsky, R. Weiss, D. Neureiter, M. Wipplinger, A. Risch, P. Hammerl, R. Greil, M. Sibilia, I. K. Gratz, P. Stoitzner, F. Aberger
This study investigates how Hedgehog signaling in skin cancer modulates immune cells and resistance to immunotherapy, identifying potential targets for combination treatments.
bioRxiv · Sep 15, 2019Cancer Biology