Author

I. K. Gratz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:human· 4 Assay:flow cytometry· 3 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

M. M. Klicznik· 4 shared D. J. Campbell· 3 shared A. Benedetti· 2 shared A. Stoecklinger· 2 shared M. D. Rosenblum· 2 shared S. Motley· 2 shared T. Duhen· 2 shared A. Risch· 1 shared

Activity by Year

2018-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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4 shared papersImmunology

M. M. Klicznik

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A novel humanized mouse model to study the function of human cutaneous memory T cells in vivo in human skin

M. M. Klicznik, A. Benedetti, L. M. Gail, S. R. Varkhande, R. Holly, M. Laimer, A. Stoecklinger, A. Sir, R. Reitsamer, T. Neuper, J. Horejs-Hoeck, M. D. Rosenblum, D. J. Campbell, E. Murauer, I. K. Gratz

This study develops a humanized mouse model to study human cutaneous memory T cells in vivo, showing their functional profiles and responses to pathogens.

bioRxiv · May 15, 2020Immunology

Transcriptomic profiling of human effector and regulatory T cell subsets identifies predictive population signatures

B. Hoellbacher, T. Duhen, S. Motley, M. M. Klicznik, I. K. Gratz, D. J. Campbell

The paper identifies transcriptional signatures of human Th and Treg cell subsets and shows their enrichment in different tissues using bulk RNA-seq data.

bioRxiv · May 13, 2020Immunology

Epidermal activation of Hedgehog signaling establishes an immunosuppressive microenvironment in basal cell carcinoma by modulating skin immunity

S. Grund-Groeschke, D. Ortner, A. Szenes-Nagy, N. Zaborsky, R. Weiss, D. Neureiter, M. Wipplinger, A. Risch, P. Hammerl, R. Greil, M. Sibilia, I. K. Gratz, P. Stoitzner, F. Aberger

This study investigates how Hedgehog signaling in skin cancer modulates immune cells and resistance to immunotherapy, identifying potential targets for combination treatments.

bioRxiv · Sep 15, 2019Cancer Biology

Human CD4+CD103+ cutaneous resident memory T cells are found in the circulation of healthy subjects

M. M. Klicznik, P. A. Morawski, B. Höllbacher, S. Varkhande, S. Motley, L. Kuri-Cervantes, E. Goodwin, M. D. Rosenblum, S. A. Long, G. Brachtl, T. Duhen, M. Betts, D. Campbell, I. K. Gratz

The paper identifies human CD4+CD103+ cutaneous resident memory T cells in circulation and shows they can migrate to distant skin sites.

bioRxiv · Mar 14, 2019 · PreprintImmunology

Circulating CD4+ memory T cells give rise to a CD69+ resident memory T cell population in non-inflamed human skin

M. M. Klicznik, A. Benedetti, A. Stoecklinger, D. J. Campbell, I. K. Gratz

The paper shows circulating CD4+ memory T cells can generate CD4+CD69+ resident memory T cells in non-inflamed human skin without infection or inflammation.

bioRxiv · Dec 9, 2018 · PreprintImmunology