A molecular atlas of proximal airway identifies subsets of known airway cell types revealing details of the unique molecular pathogenesis of Cystic Fibrosis
G. Carraro, J. Langerman, S. Sabri, Z. Lorenzana, A. Purkayastha, B. Konda, C. J. Aros, B. A. Calvert, A. Szymaniak, E. Wilson, M. Mulligan, P. Bhatt, P. Vijayaraj, C. Yao, D. W. Shia, , B. N. Gomperts
The paper uses single-cell transcriptomics to analyze proximal airway epithelium in CF and healthy donors, identifying molecular changes linked to CF pathogenesis.
Nature Medicine · May 6, 2021Peer-reviewedCell Biology