Author

D. W. Shia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:scRNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

T. M. Rickabaugh· 3 shared A. Purkayastha· 2 shared B. Konda· 2 shared B. N. Gomperts· 2 shared B. R. Stripp· 2 shared C. Sen· 2 shared J. Langerman· 2 shared K. Plath· 2 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCell Biology

T. M. Rickabaugh

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Author profile →

3 papers

Recent·Most cited

Small cell lung cancer co-culture organoids provide insights into cancer cell survival after chemotherapy

C. Sen, C. Koloff, S. Kundu, D. C. Wilkinson, J. Yang, D. W. Shia, L. K. Meneses, T. M. Rickabaugh, B. Gomperts

This paper develops a 3D SCLC co-culture organoid model to study chemotherapy resistance and fibroblast interactions in relapsed SCLC.

bioRxiv · Jan 3, 2023 · PreprintBioengineering

A molecular atlas of proximal airway identifies subsets of known airway cell types revealing details of the unique molecular pathogenesis of Cystic Fibrosis

G. Carraro, J. Langerman, S. Sabri, Z. Lorenzana, A. Purkayastha, B. Konda, C. J. Aros, B. A. Calvert, A. Szymaniak, E. Wilson, M. Mulligan, P. Bhatt, P. Vijayaraj, C. Yao, D. W. Shia, , B. N. Gomperts

The paper uses single-cell transcriptomics to analyze proximal airway epithelium in CF and healthy donors, identifying molecular changes linked to CF pathogenesis.

Nature Medicine · May 6, 2021Peer-reviewedCell Biology

Direct exposure to SARS-CoV-2 and cigarette smoke increases infection severity and alters the stemcell-derived airway repair response

A. Purkayastha, C. Sen, G. Garcia, J. Langerman, P. Vijayaraj, D. W. Shia, L. K. Meneses, T. M. Rickabaugh, A. Mulay, B. Konda, M. S. Sim, B. R. Stripp, K. Plath, V. Arumugaswami, B. N. Gomperts

This study shows that cigarette smoke exposure increases SARS-CoV-2 infection severity in airway cultures by reducing interferon response and ABSC proliferation.

bioRxiv · Jul 28, 2020Cell Biology