Biochemical characterization of actin assembly mechanisms with ALS-associated profilin variants
X. Liu, M. L. Pimm, B. Haarer, A. T. Brawner, J. L. Henty-Ridilla
This study investigates how ALS-associated profilin variants affect actin assembly through biochemical assays and finds that some variants impair actin elongation when formin is present.
bioRxiv · Jan 5, 2022Biochemistry