Author

M. L. Pimm

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:protein folding & dynamics· 1 Assay:protein sequence· 1 Organism:yeast· 1

Frequent Co-Authors

J. L. Henty-Ridilla· 4 shared B. K. Haarer· 2 shared X. Liu· 2 shared A. D. Nobles· 1 shared A. G. Marcin· 1 shared A. Lojko· 1 shared A. T. Brawner· 1 shared B. Haarer· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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4 shared papersCell Biology

J. L. Henty-Ridilla

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4 papers

Recent·Most cited

Coordination of actin plus-end dynamics by IQGAP1, formin, and capping protein

M. L. Pimm, B. K. Haarer, A. D. Nobles, L. M. Haney, A. G. Marcin, M. A. Eligio, J. L. Henty-Ridilla

This study investigates IQGAP1's role in regulating actin plus-end dynamics by displacing formin and capping protein, affecting cell morphology and migration.

bioRxiv · May 4, 2023Cell Biology

Purification of Human β and γ-actin from Budding Yeast

B. K. Haarer, M. L. Pimm, E. P. deJong, D. Amberg, J. L. Henty-Ridilla

This study develops yeast strains expressing human β- or γ-actin as their sole source, enabling purification of these actin isoforms for biochemical studies.

bioRxiv · Aug 17, 2022Biochemistry

Biochemical characterization of actin assembly mechanisms with ALS-associated profilin variants

X. Liu, M. L. Pimm, B. Haarer, A. T. Brawner, J. L. Henty-Ridilla

This study investigates how ALS-associated profilin variants affect actin assembly through biochemical assays and finds that some variants impair actin elongation when formin is present.

bioRxiv · Jan 5, 2022Biochemistry

Visualizing Molecules of Functional Human Profilin

M. L. Pimm, X. Liu, F. Tuli, J. Heritz, A. Lojko, J. L. Henty-Ridilla

The paper develops genetically encoded tagged versions of PFN1 to study its interactions with actin and microtubules in vitro and in live cells, revealing functional insights into PFN1's role in cellular processes and disease.

bioRxiv · Sep 1, 2021Cell Biology