Author

A. Tsingene

Wellcome Sanger Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:eQTL / molecular QTL mapping· 1

Frequent Co-Authors

Alice BarnettiD· 2 shared Andrew J. KnightsiD· 2 shared Carl A. AndersoniD· 2 shared Céline Gomez· 2 shared Daniel J. GaffneyiD· 2 shared Lorena Boquete VilarinoiD· 2 shared Maria ImaziD· 2 shared Natsuhiko KumasakaiD· 2 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Alice BarnettORCID

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Author profile →

3 papers

Recent·Most cited

Gene expression QTL mapping in stimulated iPSC-derived macrophages provides insights into common complex diseases.

Nikolaos I. Panousis, Omar El Garwany, Andrew J. Knights, Jesse Rop, Natsuhiko Kumasaka, Maria Imaz, Lorena Boquete Vilarino, A. Tsingene, Alex Tokolyi, Alice Barnett, Céline Gomez, Carl A. Anderson, Daniel J. Gaffney

The paper maps eQTLs in stimulated iPSC-derived macrophages and identifies condition-specific reQTLs that colocalize with disease-associated variants.

Nature Communications · Aug 27, 2025Peer-reviewedGenomics

Low-usage splice junctions underpin immune-mediated disease risk

Omar El Garwany, Nikolaos I. Panousis, Andrew J. Knights, Natsuhiko Kumasaka, Maria Imaz, Lorena Boquete Vilarino, A. Tsingene, Alice Barnett, Céline Gomez, Daniel J. Gaffney, Carl A. Anderson

The paper identifies low-usage splice junctions as contributors to immune-mediated disease risk by linking sQTLs to disease loci and showing their impact on gene expression in inflammation.

bioRxiv · May 29, 2023 · PreprintGenomics

Lung, spleen and oesophagus tissue remains stable for scRNAseq in cold preservation

Elo Madissoon, Anna Wilbrey-Clark, Ricardo J. Miragaia, Kourosh Saeb‐Parsy, Krishnaa T. A. Mahbubani, Nikitas Georgakopoulos, P. Harding, Krzysztof Polański, Karol Nowicki-Osuch, Rebecca Claire Fitzgerald, Kevin W. Loudon, John Robert Ferdinand, Menna Ruth Clatworthy, A. Tsingene, Stijn van Dongen, , Kerstin B. Meyer

This study evaluates the impact of cold storage on scRNAseq data quality for lung, spleen, and oesophagus tissues, finding minimal effects within 24 hours but increased stress markers at 72 hours.

bioRxiv · Aug 31, 2019 · PreprintGenomics