Elo Madissoon

This paper benchmarks the Ultima UG100 and Illumina NovaSeq platforms on FFPE tissues for various sequencing modalities, finding they produce comparable results with subtle discrepancies in non-coding transcripts.

The paper identifies a prognostic infiltration zone in glioblastoma using histology and spatial transcriptomic integration, revealing specific cell composition associated with long-term survival.

The paper compares three transcriptomic methods on FFPE tumor samples to assess their ability to detect inter- and intra-patient heterogeneity.

The paper constructs a human fetal lung cell atlas from 5-22 post conception weeks, identifying new cell states and regulators of epithelial fates.

Across 1,176,683 airway and lung cells from 22 datasets, ACE2 rises with age, in males and in smokers' multiciliated cells, and is lowest in young children.

This study evaluates the impact of cold storage on scRNAseq data quality for lung, spleen, and oesophagus tissues, finding minimal effects within 24 hours but increased stress markers at 72 hours.

The paper identifies a conserved DNA motif bound by PLAG1 that regulates zygotic genome activation in mice and humans, affecting early embryo development.

The paper generates a single-cell RNA-seq dataset of HeLa cells labeled with Fucci reporters and provides an open workflow for data processing and quality control.