Author

A. Uguen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:imaging· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

J.-O. Pers· 2 shared M. Le Rochais· 2 shared P. Hemon· 2 shared S. Garaud· 2 shared A. Abou-Ammoud· 1 shared A. Jabouille· 1 shared A. Pham-Ledart· 1 shared A. Tison· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersImmunology

J.-O. Pers

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

B-Cell Involvement in Immune Checkpoint Inhibitor-Induced Lichen Planus: A Comparative Analysis with Non-Drug-Related Lichen Planus.

A. Tison, D. Legoupil, M. Le Rochais, P. Hemon, N. Foulquier, Q. Hardy, S. Hillion, A. Uguen, J.-O. Pers, L. Misery, D. Cornec, S. Garaud

This study compares immune infiltration in ICI-induced lichen planus and non-drug-related lichen planus, finding reduced T-cell infiltration and increased B-cell frequency in the former.

bioRxiv · Jan 4, 2024Immunology

Deciphering the maturation of tertiary lymphoid structures in cancer and inflammatory diseases of the digestive tract using imaging mass cytometry: from high-level data to a simple architectural and functional grading

M. Le Rochais, P. Hemon, D. Ben-Guigui, S. Garaud, C. Le Dantec, J.-O. Pers, A. Uguen

This paper uses imaging mass cytometry to analyze tertiary lymphoid structures in digestive tract diseases, revealing a three-stage maturation grading based on architectural and functional markers.

bioRxiv · Nov 15, 2022 · PreprintImmunology

Discoidin domain receptor 2 drives melanoma drug resistance through AXL-dependent phenotype switching

M. Sala, N. Allain, A. Jabouille, E. Henriet, A. Abou-Ammoud, A. Uguen, S. Di-Tommaso, D. Cyril, A.-A. Raymond, J.-W. Dupuy, E. Gerard, N. Dugot-Senant, B. Rousseau, J.-P. Merlio, A. Pham-Ledart, , F. Saltel

This study shows DDR2 drives melanoma drug resistance via AXL-dependent phenotype switching, suggesting DDR inhibition as a potential second-line treatment.

bioRxiv · Mar 26, 2021 · PreprintCancer Biology