Emerging role of oncogenic β-catenin in exosome biogenesis as a driver of immune escape in hepatocellular carcinoma
C. Dantzer, J. Vache, A. Brunel, I. Mahouche, A.-A. Raymond, J.-W. Dupuy, M. Petrel, P. Bioulac-Sage, D. Perrais, N. Dugot-Senant, M. Verdier-Sage, B. Bessette, C. Billottet, V. Moreau
This study shows that oncogenic β-catenin reduces exosome release in HCC, leading to immune escape by decreasing immune cell infiltration.
bioRxiv · Oct 24, 2023Cancer Biology