Author

A. van Oijen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Assay:fluorescence / live-cell microscopy· 1 Approach:microscopy & imaging analysis· 1 Assay:protein sequence· 1

Frequent Co-Authors

B. Paudel· 2 shared J. Low· 2 shared J. Mackay· 2 shared Y. Zhong· 2 shared A. Silva· 1 shared B. P. Paudel· 1 shared C. Deshpande· 1 shared C. Franck· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersBiochemistry

B. Paudel

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The role of auxiliary domains in modulating CHD4 activity suggests mechanistic commonality between enzyme families

Y. Zhong, H. Moghaddas Sani, B. Paudel, J. Low, A. Silva, S. Mueller, C. Deshpande, S. Panjikar, X. Reid, M. Bedward, A. van Oijen, J. Mackay

The paper investigates how auxiliary domains in CHD4 modulate its activity, revealing common regulatory mechanisms across chromatin remodelling enzyme families.

bioRxiv · Jun 13, 2022 · PreprintBiochemistry

Real-time single-molecule observation of chaperone-assisted protein folding

N. Marzano, B. Paudel, A. van Oijen, H. Ecroyd

This study uses single-molecule techniques to observe Hsp70 chaperone interactions during protein folding, revealing binding cycles and distinct mechanisms for DnaJ and DnaK.

bioRxiv · May 9, 2022Biochemistry

CHD4 slides nucleosomes by decoupling entry- and exit-side DNA translocation

Y. Zhong, B. P. Paudel, D. Ryan, J. Low, C. Franck, K. Patel, M. Benward, R. Payne, A. van Oijen, J. Mackay

This study investigates the mechanism of CHD4-mediated nucleosome sliding using single-molecule assays, revealing a decoupling of DNA translocation at entry and exit sides.

bioRxiv · Jun 27, 2019Biochemistry