Palmitoylation targets the Calcineurin phosphatase to the Phosphatidylinositol 4-kinase complex at the plasma membrane
I. Ulengin-Talkish, M. A. Parson, M. L. Jenkins, J. Roy, A. Z. Shih, N. St-Denis, G. Gulyas, T. Balla, A.-C. Gingras, P. Varnai, E. Conibear, J. E. Burke, M. S. Cyert
This study identifies palmitoylation as a mechanism that localizes CNA{beta}1 to the plasma membrane and Golgi, enabling its interaction with the PI4KA complex and regulating PI4P production.
bioRxiv · Jul 14, 2021Biochemistry