Author

T. Balla

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Cell Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:imaging· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

J. G. Pemberton· 4 shared J. E. Burke· 3 shared M. L. Jenkins· 3 shared M. A. Parson· 2 shared A. A. Prats· 1 shared A. Eisenreichova· 1 shared A. L. Shaw· 1 shared A. R. Mantegazza· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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4 shared papersBiochemistry

J. G. Pemberton

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Author profile →

6 papers

Recent·Most cited

Molecular basis for plasma membrane recruitment of PI4KA by EFR3

S. Suresh, A. L. Shaw, J. G. Pemberton, M. K. Scott, N. J. Harris, M. A. Parson, M. L. Jenkins, P. Rohilla, A. A. Prats, T. Balla, C. K. Yip, J. E. Burke

The paper reports a cryo-EM structure of EFR3A bound to the PI4KA complex, revealing the molecular mechanism of PI4KA membrane recruitment and its regulation in human disease.

bioRxiv · Apr 30, 2024 · PreprintBiochemistry

Defining the EM-signature of successful cell-transfection

J. G. Pemberton, T. Tenkova, P. L. Felgner, J. Zimmerberg, T. Balla, J. E. Heuser

The paper uses electron microscopy to identify unique structural changes in cells after transfection with Lipofectamine 2000 and 3000, providing a method to distinguish successfully transfected cells.

bioRxiv · Mar 7, 2024 · PreprintCell Biology

Palmitoylation targets the Calcineurin phosphatase to the Phosphatidylinositol 4-kinase complex at the plasma membrane

I. Ulengin-Talkish, M. A. Parson, M. L. Jenkins, J. Roy, A. Z. Shih, N. St-Denis, G. Gulyas, T. Balla, A.-C. Gingras, P. Varnai, E. Conibear, J. E. Burke, M. S. Cyert

This study identifies palmitoylation as a mechanism that localizes CNA{beta}1 to the plasma membrane and Golgi, enabling its interaction with the PI4KA complex and regulating PI4P production.

bioRxiv · Jul 14, 2021Biochemistry

Phosphatidylinositol-4-kinase IIα licenses phagosomes for TLR4 signaling and MHC-II presentation in dendritic cells

C. Lopez-Haber, R. Levin-Konigsberg, Y. Zhu, J. Bi-Karchin, T. Balla, S. Grinstein, M. S. Marks, A. R. Mantegazza

This study identifies PI4KII as essential for phagosomal TLR4 signaling and MHC-II presentation in dendritic cells by facilitating TIRAP recruitment.

bioRxiv · Jan 22, 2020Cell Biology

Defining the Subcellular Distribution and Metabolic Channeling of Phosphatidylinositol

J. G. Pemberton, Y. J. Kim, N. Sengupta, A. Eisenreichova, D. J. Toth, E. Boura, T. Balla

The paper defines the subcellular distribution and metabolic channeling of phosphatidylinositol using a bacterial enzyme to study its dynamics in intact cells.

bioRxiv · Jun 20, 2019Cell Biology

Characterisation of the c10orf76-PI4KB complex, and its necessity for Golgi PI4P levels and enterovirus replication

J. A. McPhail, H. Lyoo, J. G. Pemberton, R. M. Hoffmann, W. van Elst, J. R. P. M. Strating, M. L. Jenkins, J. Stariha, F. J. M. van Kuppeveld, T. Balla, J. E. Burke

This study characterizes the c10orf76-PI4KB complex, showing its role in maintaining Golgi PI4P levels and enabling enterovirus replication.

bioRxiv · May 10, 2019Biochemistry