Disruption of IL-17 signaling in the respiratory mucosa results in invasive streptococcal infection
M. Pandey, J.-L. Mills, A. Lepletier, V. Ozberk, J. Dooley, J. Kaden, A. Calcutt, Y. Huo, A. Hicks, A. Zaid, M. Good
This study shows that IL-17 deficiency in mice leads to increased S. pyogenes dissemination after respiratory infection, contributing to invasive streptococcal disease.
bioRxiv · Nov 10, 2023 · PreprintImmunology