Author

A. Zana

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:metabolomics· 1

Frequent Co-Authors

D. Neri· 3 shared J. Millul· 3 shared S. Cazzamalli· 3 shared A. Galbiati· 2 shared A. Elsayed· 1 shared A. Villa· 1 shared C. Krudewig· 1 shared E. Gilardoni· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersPharmacology & Toxicology

D. Neri

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3 papers

Recent·Most cited

A mass spectrometry-based method for the determination of in vivo biodistribution of tumor targeting small molecule-metal conjugates

E. Gilardoni, A. Zana, A. Galbiati, T. Sturm, J. Millul, S. Cazzamalli, D. Neri, R. Stucchi

The paper develops a mass spectrometry-based method to quantify tumor-targeting small molecule-metal conjugates and validates it against radioactive biodistribution data.

bioRxiv · Mar 4, 2022Pharmacology & Toxicology

A novel dimeric FAP-targeting small molecule-radio conjugate with high and prolonged tumour uptake

A. Galbiati, A. Zana, M. Bocci, J. Millul, A. Elsayed, J. Mock, D. Neri, S. Cazzamalli

This paper develops a dimeric FAP-targeting radioligand with prolonged tumour uptake and improved tumour-to-organ ratio, showing potent anti-tumour efficacy in preclinical models.

bioRxiv · Feb 21, 2022Pharmacology & Toxicology

Immunotherapy with immunocytokines and PD-1 blockade enhances the anticancer activity of small molecule-drug conjugates targeting carbonic anhydrase IX

J. Millul, C. Krudewig, A. Zana, S. Dakhel Plaza, E. Puca, A. Villa, D. Neri, S. Cazzamalli

This study shows that combining SMDCs targeting carbonic anhydrase IX with immunotherapy enhances anticancer activity in mouse models of renal cell carcinoma and colorectal cancer.

bioRxiv · Jun 3, 2020Cancer Biology