PLB-985 neutrophil-like cells as a model to study Aspergillus fumigatus pathogenesis
M. Rafiq, F. Rivieccio, A.-K. Zimmermann, C. Visser, A. Bruch, T. Krüger, K. Gonzalez Rojas, O. Kniemeyer, M. G. Blango, A. A. Brakhage
This paper demonstrates that differentiated PLB-985 cells can model key aspects of A. fumigatus interactions with human neutrophils, including phagocytosis, extracellular trap release, and antifungal vesicle production.
bioRxiv · Jul 28, 2021Microbiology