Serpine1 negatively regulates Th1 cell responses in experimental autoimmune encephalomyelitis.
I. Akbar, R. Tang, J. Baillargeon, A.-P. Roy, P. M. I. A. Doss, C. Zhu, V. K. Kuchroo, M. Rangachari
This study shows Serpine1 inhibits Th1 cell pathogenicity in EAE by promoting Tim-3 expression and function.
bioRxiv · Jul 13, 2023 · PreprintImmunology