Myelin-reactive B cells exacerbate the severity of CD4+ T cell-driven CNS autoimmunity in an IL-23-dependent manner.
M. R. Fazazi, P. M. I. A. Doss, R. Pereira…·M. Rangachari
This study shows that MOG-specific B cells worsen CD4+ T cell-driven CNS autoimmunity by promoting Th17 and Tph cell accumulation via IL-23.