MAFA drives pancreatic islet maturation through coordination of cell growth, metabolic maturation, and resilience to stress.
Veronica A. Cochrane, Michael Sterr, Marianne Aniag, Sara Jiménez, Madeline S. Wang, Ying Liu, Alena Boos, Juliane Merl‐Pham, Aarti Anand, Ryan E. Hoang, Rachita Gupta, Heiko Lickert, Tiago C. Alves, Jeeyeon Cha, Roland Stein, , Matthias Hebrok
This study shows that MAFA promotes pancreatic islet maturation by enhancing cell growth, metabolic function, and stress resilience in stem cell-derived islets.
bioRxiv · Sep 30, 2026 · PreprintCell Biology