Author

Aathavan S. Uruthirapathy

Western University

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Biology Disciplines

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Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Claire Shuiqing ZhangiD· 1 shared David E. HeinrichsiD· 1 shared David R. EdgelliD· 1 shared Gary W. FooiD· 1 shared Izabela Z. Batko· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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1 shared paperSynthetic Biology

Claire Shuiqing ZhangORCID

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1 paper

Recent·Most cited

Genetic entanglement enables ultra-stable biocontainment in the mammalian gut

Gary W. Foo, Aathavan S. Uruthirapathy, Claire Shuiqing Zhang, Izabela Z. Batko, David E. Heinrichs, David R. Edgell

The paper introduces STALEMATE, a biocontainment system that reduces genetic escape rates in engineered bacteria by entangling genetic sequences, achieving rates below 10^-10 in mice.

ACS Synthetic Biology · Sep 7, 2025Peer-reviewedSynthetic Biology