Author

Claire Shuiqing Zhang

Western UniversityORCID 0000-0003-3866-602XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1

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Aathavan S. Uruthirapathy· 1 shared David E. HeinrichsiD· 1 shared David R. EdgelliD· 1 shared Gary W. FooiD· 1 shared Izabela Z. Batko· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperSynthetic Biology

Aathavan S. Uruthirapathy

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1 paper

Recent·Most cited

Synthetic BiologyACS Synthetic BiologyPeer-reviewedSep 7, 2025

Genetic entanglement enables ultra-stable biocontainment in the mammalian gut

Gary W. Foo, Aathavan S. Uruthirapathy, Claire Shuiqing Zhang…·David R. Edgell

The paper introduces STALEMATE, a biocontainment system that reduces genetic escape rates in engineered bacteria by entangling genetic sequences, achieving rates below 10^-10 in mice.

4 citations

mouseexperimental assay

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