Author
Western UniversityORCID 0009-0006-3670-6672Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Vida Nasrollahi, Gary W. Foo, Tahani Jaafar…·Bogumil Jacek Karas
The paper sequences two Campylobacter jejuni strains and develops a plasmid system to enhance genetic tools for studying clinical isolates.
Gary W. Foo, Aathavan S. Uruthirapathy, Claire Shuiqing Zhang…·David R. Edgell
The paper introduces STALEMATE, a biocontainment system that reduces genetic escape rates in engineered bacteria by entangling genetic sequences, achieving rates below 10^-10 in mice.
Dalton T. Ham, Tyler S. Browne, Claire Q. Zhang…·David R. Edgell
This study uses machine learning to predict SaCas9 activity in bacteria, revealing that PAM adenine methylation and flanking sequences significantly influence activity.
Gary W. Foo, Christopher D. Leichthammer, Ibrahim M. Saita…·David R. Edgell
The paper develops thermoregulated meganucleases to degrade DNA at 18°C, preventing the spread of engineered genetic material outside the mammalian gut.