A human synovial tendon-on-a-chip models key features of peritendinous adhesions and offers a new approach methodology for testing anti-fibrotic drugs
Isabelle Linares, Anabelle Creveling, Abdikadir Osman, Nathan Grandwetter, Benjamin L. Miller, James L. McGrath, Hani A. Awad
This paper develops a human synovial tendon-on-a-chip model to study peritendinous adhesions and test anti-fibrotic drugs, showing IL-6 inhibition reduces fibrosis and adhesion formation.
bioRxiv · Apr 7, 2026 · PreprintBioengineering