Author

Isabelle Linares

University of Rochester MedicineORCID 0009-0004-6720-2528Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Benjamin L. MilleriD· 2 shared Hani A. AwadiD· 2 shared James L. McGrathiD· 2 shared Abdikadir Osman· 1 shared Anabelle Creveling· 1 shared Ava Saffren· 1 shared Kaihua CheniD· 1 shared Mehran MansouriiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBioengineering

Benjamin L. MillerORCID

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2 papers

Recent·Most cited

BioengineeringbioRxivPreprintApr 7, 2026

A human synovial tendon-on-a-chip models key features of peritendinous adhesions and offers a new approach methodology for testing anti-fibrotic drugs

Isabelle Linares, Anabelle Creveling, Abdikadir Osman…·Hani A. Awad

This paper develops a human synovial tendon-on-a-chip model to study peritendinous adhesions and test anti-fibrotic drugs, showing IL-6 inhibition reduces fibrosis and adhesion formation.

DOI 10.64898/2026.04.03.716316

humanexperimental assay

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BioengineeringScientific ReportsPeer-reviewedJan 25, 2025

Fluid Flow Impacts Endothelial-Monocyte Interactions in a Model of Vascular Inflammatory Fibrosis

Isabelle Linares, Kaihua Chen, Ava Saffren…·James L. McGrath

This study shows that adding physiological flow to a human tendon-on-a-chip model increases endothelial activation and monocyte infiltration, highlighting the role of flow in immune cell interactions during inflammation.

21 citationstop 1%

humanexperimental assay

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