Thermally controlled state switches for macrophage immunotherapy
Ann Liu, Abdullah S. Farooq, Mohamad H. Abedi, Cameron A. B. Smith, Di M. Wu, Mikhail G. Shapiro
This paper designs a thermal bioswitch to control macrophage activation in vivo, enabling spatially localized gene expression for at least 14 days after ultrasound heating.
bioRxiv · Jun 9, 2025 · PreprintBioengineering