Alcohol Use Disorder Associated Gene FNDC4 Alters Glutamatergic and GABAergic Neurogenesis
Xiujuan Zhu, August J. John, Li Wang, Sooan Kim, Enci Ding, Ateka Saleh, Irene Marín-Goñi, Abedalrahman Jomaa, Huanyao Gao, Ching Man Wai, Irene Moon, Brandon J. Coombes, Tony M. Kerr, Nobuyoshi Suto, Liewei Wang, , Duan Liu
The paper identifies FNDC4 as a gene associated with alcohol use disorder through GWAS and shows its role in regulating neurogenesis via alternative splicing and CRISPR/Cas9 experiments.
bioRxiv · May 15, 2025 · PreprintGenomics