A sequence motif for DNA double-strand break and telomere healing during programmed DNA elimination
Jansirani Srinivasan, Marro Agbaga, Vincent Terta, Brandon Estrem, James Ryan Simmons, Ryan Oldridge, Mehwish Iftikhar, Abigail West, Hannah Bou-Lai Lam, Thomas C. Dockendorff, Jianbin Wang
The paper identifies a sequence motif, SFE, that is necessary and sufficient for generating DNA double-strand breaks and telomere healing during programmed DNA elimination in nematodes.
bioRxiv · Mar 9, 2026 · PreprintGenetics