Jianbin Wang

The paper identifies a sequence motif, SFE, that is necessary and sufficient for generating DNA double-strand breaks and telomere healing during programmed DNA elimination in nematodes.

The paper identifies two Argonautes in Ascaris linked to programmed DNA elimination, showing their siRNAs target different genomic regions during chromosome remodeling.

The paper investigates spatial genome organization during programmed DNA elimination in nematodes, showing conserved 3D genome reorganization across species.

The paper studies DNA double-strand breaks (DSBs) during nematode programmed DNA elimination, showing that DSBs are processed with end resection and telomere addition, with biased repair on retained ends.

The paper investigates programmed DNA elimination (PDE) in parasitic nematodes, showing how it leads to karyotype changes through chromosome fusion and DNA loss.

This paper establishes Oscheius tipulae as a genetic model for studying programmed DNA elimination (PDE) and identifies conserved motifs and mechanisms involved in DNA loss during embryogenesis.

The paper analyzes small RNA pathways in the parasitic nematode Ascaris, revealing their roles in gene regulation and target plasticity during spermatogenesis.

The paper maps DNA elimination in Ascaris by analyzing germline and somatic genomes, revealing chromosome end remodeling and telomere healing during programmed DNA elimination.

The paper shows helminths switch from ubiquinone to rhodoquinone synthesis via alternative splicing of coq-2 in anaerobic environments.

The paper identifies region-specific regulation of stem cell-driven regeneration in tapeworms, showing that extrinsic signals from the head and neck control regeneration without stem cell restriction to the neck.