Aging-associated long non-coding RNA boosts longevity and reduces the ribosome content of non-dividing fission yeast cells
Shajahan Anver, Ahmed Faisal Sumit, Xi-Ming Sun, Abubakar A. Hatimy, Konstantinos Thalassinos, Samuel Marguerat, Nazif Alic, Jürg Bähler
This study identifies a lncRNA, aal1, that extends lifespan in fission yeast by reducing ribosome content and protein translation, with similar effects observed in Drosophila.
EMBO Reports · Oct 2, 2024Peer-reviewedGenetics