Temperature-Dependent Fold-Switching Mechanism of the Circadian Clock Protein KaiB
Ning Zhang, Damini Sood, Spencer C. Guo, Nanhao Chen, Adam Antoszewski, Tegan Marianchuk, Archana Chavan, Supratim Dey, Yunxian Xiao, Lu Hong, Xiangda Peng, Michael Baxa, Carrie Partch, Lee-Ping Wang, Tobin R. Sosnick, , Andy LiWang
This study investigates how temperature affects the fold-switching mechanism of KaiB, a circadian clock protein, showing that proline isomerization is a rate-limiting step.
bioRxiv · May 21, 2024 · PreprintBiochemistry