Cancer BiologybioRxivPreprint
Combined inhibition of mTOR and PIKKs exploits replicative and checkpoint vulnerabilities to induce death of PI3K-activated triple-negative breast cancer cells
Sameer S. Chopra, Anne Jenney, Adam Palmer…·Peter K. Sorger
The paper shows that combining mTOR and PIKK inhibitors kills triple-negative breast cancer cells by exploiting replication and checkpoint vulnerabilities.
DOI 10.1101/700625