Identification of potential treatments for COVID-19 through artificial intelligence-enabled phenomic analysis of human cells infected with SARS-CoV-2
Katie Heiser, Peter McLean, Chadwick T. Davis, Ben Fogelson, Hannah B. Gordon, Pamela Jacobson, Brett L. Hurst, Ben Miller, Ronald W. Alfa, Berton A. Earnshaw, Mason L. Victors, Yolanda T. Chong, Imran S. Haque, Adeline S. Low, Christopher C. Gibson
In an image-based screen of 1,670 compounds in SARS-CoV-2-infected human renal epithelial cells, remdesivir was the only antiviral with strong efficacy; chloroquine and hydroxychloroquine showed no benefit.
bioRxiv · Apr 21, 2020 · PreprintSystems Biology