Christopher C. Gibson

The paper identifies a proximity bias in CRISPR-Cas9 knockouts, showing phenotypic similarity between unrelated genes on the same chromosome arm, and proposes a correction method.

In an image-based screen of 1,670 compounds in SARS-CoV-2-infected human renal epithelial cells, remdesivir was the only antiviral with strong efficacy; chloroquine and hydroxychloroquine showed no benefit.