DAXX safeguards heterochromatin formation in embryonic stem cells
Antoine Canat, Adeline Veillet, Renaud Batrin, Clara Dubourg, Priscillia Lhoumaud, Pol Arnau-Romero, Max Greenberg, Frédéric Bonhomme, Paola Barbara Arimondo, Robert Scott Illingworth, Emmanuelle Fabre, Pierre Therizols
This study identifies DAXX's role in maintaining heterochromatin structure in ESCs by recruiting PML and SETDB1, and shows its importance for genome integrity and pluripotency.
Journal of Cell Science · Sep 1, 2023Peer-reviewedMolecular Biology