Priscillia Lhoumaud

The paper identifies a developmentally regulated long-range enhancer-promoter contact that is critical for SOX2 expression and neuroectodermal differentiation in human neural development.

The paper uses Methyl-ATAC and Methyl-CUT&Tag to study 5mC and 5hmC dynamics during mESC differentiation, revealing their role in enhancer regulation.

The paper investigates how CTCF mutations affect chromatin accessibility, cohesin binding, and gene regulation through multivariate modeling and mutant perturbations.

This study identifies DAXX's role in maintaining heterochromatin structure in ESCs by recruiting PML and SETDB1, and shows its importance for genome integrity and pluripotency.

The paper identifies new therapeutic targets in CRLF2-overexpressing B-ALL by analyzing TF-gene regulatory interactions using network inference and experimental validation.

EpiMethylTag combines ATAC-seq or ChIP-seq with bisulfite conversion to simultaneously assess chromatin accessibility/TF binding and DNA methylation.

The paper shows NSD2 overexpression alters chromatin structure and gene expression by affecting CTCF and H3K27ac in specific chromatin domains.