Copy Number Variation at 16p11.2 Imparts Transcriptional Alterations in Neural Development in an hiPSC-derived Model of Corticogenesis
Julien George Roth, Kristin L. Muench, Aditya Asokan, Victoria M Mallett, Hui Gai, Yogendra Verma, Stephen G. Weber, Carol A. Charlton, Jonas L. Fowler, Kyle M. Loh, Ricardo E. Dolmetsch, Theo D. Palmer
The paper generates 65 hiPSC clones with 16p11.2 CNVs and identifies transcriptional changes in neural development using RNA-Seq.
bioRxiv · Apr 22, 2020 · PreprintNeuroscience