Author
Aligning Science Across Parkinson'sORCID 0000-0003-3380-6089Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Oriol Busquets, Hanqin Li, Khaja Mohieddin Syed…·Frank Soldner
The paper generates a collection of 65 isogenic human stem cell lines with PD-associated mutations to study Parkinson's disease, revealing that most genetic variation comes from cell culture rather than genome editing.
Hanqin Li, Oriol Busquets, Yogendra Verma…·Frank Soldner
This paper compares prime editing efficiency to conventional methods in human pluripotent stem cells, showing higher efficiency with optimized mRNA delivery for mutation correction and introduction.
Julien George Roth, Kristin L. Muench, Aditya Asokan…·Theo D. Palmer
The paper generates 65 hiPSC clones with 16p11.2 CNVs and identifies transcriptional changes in neural development using RNA-Seq.